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ecombinantCOVID-19vaccinedevelopedbyChineseresearchers,CCTVreportedonWednesday. DevelopedbyateamledbyMajorGeneralChenWei,academicianatthePeople'sLiberationArmy(PLA)AcademyofMilitaryMedicalSciences,thevaccinewasoneofthefirsttoenterthefirstandthenthesecondphaseofc3

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linicaltrialsdomesticallyandinternationally. OnJanuary26,ChenledateamtoWuhanincentralChina'sHubeiProvincetofighttheepidemiconthefrontline.AfterarrivinginWuhan,Chen'steamstartedbuildingaportabletestinglab,whichstartedoperationonJanuary30.Thelabsoonac9

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hievedthetestingcapabilityof1,000peopleperday. OnMarch16,theCOVID-19vaccinedevelopedbyChenandherteambecamethefirsttobeapprovedbyChinaforclinicaltrials. ThevaccineenteredthesecondphaseofclinicaltrialsonApril12.ItisthefirstCOVID-19vaccineintheworldthatenteredthesecondphaseofclinicaltrials,accordingtotheWorldHealthOrganization. "Alargeamount AcoronavirusvaccinecandidatedevelopedbyaunitofChinaNationalPharmaceuticalGroup(Sinopharm)appearedtobesafeandtriggeredantibody-basedimmuneresponsesinearlyandmid-stagetrials,researcherssaid. Thecandidatehasalreadymovedintoalate-stagetrial,oneofahandfulofcandidatesbeingtestedonseveralthousandpeopletoseeiftheyareeffectiveenoughtowinregulatoryapproval. Sinopharmd

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istestingthepotentialvaccineintheUnitedArabEmiratesinaPhase3trialexpectedtorecruit15,000people,asChinahastoofewnewcasestobeausefultrialsite. Thestate-ownedcompanywillalsosupplythecandidatetoPakistanaspartofatrialagreement,theWallStreetJournalreported. Theshotdidnotcauseanyserioussideeffects,accordingtoapaperpublishedonThursdayintheJournaloftheAmericanMedicalAssociation(JAMA)byscientistswhoarepartofSinopharmandotherChina-baseddiseasecontrolauthoritiesandresearchinstitutes. Theresultswerebasedondatafrom320healthyadultsinPhase1and2trials. Thecandidatetriggeredrobustantibodyresponsesininoculatedpeople,butitremainedunknownifthatwassufficienttopreventCOVID-19infection,researchersdevelopingthL

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aidinthepaper. Sinopharm'schairmantoldmedialastmonththatapotentialvaccinecouldbereadybytheendofthisyearwithPhase3testingexpectedtobecompletedinaboutthreemonths. Thenovelcoronavirus,whichhaskilledmorethan750,000peopleglobally,haspromptedaracetodevelopavaccine.Moret1

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han150candidatevaccinesarebeingdevelopedandtestedaroundtheworld. Russiabecamethefirstcountrytograntregulatoryapprovaltoavaccineafterlessthantwomonthsofhumantesting,andashotdevelopedbyChinesefirmCanSinoBilogicshasbeenclearedforuseinthemilitary. Chinaisleadingthedex

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velopmentofatleasteightvaccinecandidatesindifferentstagesofclinicaltrials. ofresearchneedstobedonebeforewestartclinicaltrialssoastominimizerisks,"ChentoldCCTVinaninterviewonWednesday. Chenandherteamtookastep-wiseapproachinclinicaltrials,startingwiththeminimumdosew

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